Wowowee has broadcast episodes from other locations in the Philippines, and has also went on World Tours to other countries such as Hawaii, the United States, Australia, Guam, and upcoming shows to Winnipeg, Canada, Dubai, Houston,Texas and London, UK.
Alay sa Kapamilya was a program organized by ABS-CBN as an observation for the PhilSports Arena stampede victims. It preempted Wowowee for six days while the network decided over the fate of the variety show. The shows were a solemn tribute to the victims, featuring performances by ABS-CBN regulars. Eventually, ABS-CBN decided to temporarily cancel the variety show until its return on March 11, 2008.
In the leadup to the March 11, 2006 relaunch of Wowowee, ABS-CBN aired a 5 episode drama miniseries entitled Pangarap at Tagumpay, Mga Kwento Sa Likod ng Wowowee (Dreams and Success, The Stories Behind Wowowee). The five-episode drama package was broadcast March 6 to March 10, 2006 in Wowowee's usual timeslot. The show dramatized the lives of past winners and how their lives had changed since their appearance on the show
In several occasions, the show has paid tribute to Overseas Filipino Workers (OFW's) serving across the world. On the August 2, 2006 episode, Wowowee with cooperation with the Overseas Workers Welfare Administration (OWWA) produced a special edition saluting and featuring female OFW's who returned from Lebanon where a war was present in that country. They were all invited to attend and even participate in the show that day. The contestants during the first half that day were close friends of the OFWs, while an unspecified number of OFW's participated in "The Ultimate Pera O Bayong". All the winnings won in during the show were combined together and evenly distributed to all of the OFWs in the audience, with the grand total of winnings being PhP 1,390,000.
On September 1, 2007, about Five Hundred (500) soldiers came in full force to television noontime show Wowowee. Representatives from the Major Services, AFPWSSUS and Technical Services come to play and have fun during the show and take a crack at the grand prizes in different games.
Highlights of the event were the interviews with the loved ones of Marines who lost their lives in the fight against the Abu Sayaff Group/ MILF rebels in Basilan last July 10 and August 11, 2007. Tearfully, loved ones recounted their last communication with the fallen Marines. Host Willie Revillame also asked each of them for a short message and everybody was moved to tears during the emotion-filled moment. AFP, PIO Chief LTC Bartolome Bacarro held back his tears but could not help it, just like the rest. Emotions rose again when candles were lit for the Marines.